The Central Nervous System is denounced to various malevolent disorders. Central Nervous System covers its mechanism, Metastatic pestilence, Ramification, Cancers, Neurons and Sensory Receptors, Neurological Disorders, Neurodegenerative disease and Imaging agents to CNS neurofibroma. Cancer spreads to the Nervous System by direct invasion or compression from continuous tissues relates to the proximity of the Nervous System to other structures.
Global Central Nervous System Drugs market to grow at a CAGR of -3.2% over the period 2011-2015. The global central nervous system (CNS) therapeutics peddle has been forecast to reach US$133 billion by the year 2018, which increases in disease ubiquity rates due to increase in population, the introduction of new drugs, and increased outgo on healthcare.
Brain Tumor occurs when abnormal cells from within the brain. The symptoms of Brain stem tumors vary greatly and can include Ataxia, Cranial Nerve Palsy, headaches, problems with speech and swallowing, hearing loss, weakness, Hemiparesis, vision abnormalities, ptosis, and behavioural changes. Another possible symptom is vomiting. Any brain tumor is inherently serious and life-threatening because of its invasive and infiltrative character in the limited space of the Intracranial Cavity.
Neoplasm is an abnormal growth of tissue, which forms a mass that commonly referred to as a Tumor. Neoplasm can be caused by an Abnormal Proliferation of Tissues, that which can be caused by Genetic mutations. Not all types of Neoplasms cause a tumorous overgrowth of tissue. Malignant Neoplasms derived from epithelial cells are called Carcinomas.
Meningioma is referred to as slow-growing Brain tumors, but their origin is not from the Brain tissue. Meningiomas are often benign tumors arising from the Arachnoidal cells of Meninges of the brain and spinal cord. Meningiomas usually grow inward slowly, causing pressure on the Brain or Spinal cord. They interfere with the normal functions of the Brain after reaching a large size. They represent about one-third of all Primary Brain Tumors and occur most frequently in middle-aged women.
Gangliocytomas are rare indolent CNS tumours which are made up of mature neurons arising anywhere within the Neuroaxis. They differ from gangliogliomas as they lack neoplastic glial cells. Treatment involves surgical removal of the tumor. These are Neuroepithelial Tumors which line the ventricles of the brain and produces Cerebrospinal fluid.
Choroid Plexus Tumor arises from Brain tissue that invades nearby tissue and spread widely via the cerebrospinal fluid. Like other brain tumors, choroid plexus tumors are also “graded.” Like other Brain Tumors, Choroid Plexus Tumors are also “graded.” Choroid Plexus Neoplasms are rare, Intraventricular, Primary Central Nervous System (CNS) tumors derived from Choroid Plexus Epithelium that are seen predominantly in children.
Brainstem glioma is an aggressive and dangerous Cancerous Glioma Tumor in the brainstem which starts in the Brain or Spinal cord tissue and typically spread throughout the Nervous System. It is more diagnosed in children and young adults under the age of twenty. Symptoms of Brainstem glioma can develop slowly and subtly and may go unnoticed for months. A sudden onset of symptoms tends to occur with more rapidly growing, high-grade tumors. In other cases, the symptoms may arise abruptly. Unlike most Brain tumors, Brainstem Glioma is not often treated with Neurosurgery due to complications in vital parts of the Brain. Without treatment, the life expectancy is typically a few months from the time of diagnosis.
The Psychosocial and Neurocognitive functioning of several cancer patients and survivors deleteriously affected by various treatments of Malignant tumors such as Chemotherapy, Radiotherapy and Hormonal therapy. Oncology researchers and Clinicians are increasingly Cognizant of the negative effects of Cancer and its treatments on the Brain and its mental processes and Cognitive outcomes.
Neuropsychology in Cancer features the current findings on the Neuropsychological effects of the Cancers and their treatments along with the most promising Neuropsychological and behavioural health interventions available to mitigate these deficits.
Para Neoplastic Neurological Syndromes (PNS) are defined as the remote effects of cancer on the Nervous System. They are due to the presence of Cancer and exclusion of other known causes of the Neurological symptoms, but this criterion does not separate “true” PNS from Neurological syndromes that are coincidental with a Cancer.
The Response Assessment in Neuro-Oncology (RANO) Working Group is an international, Multidisciplinary effort to develop new standardized response criteria for Clinical trials in Brain tumors. The Surgery Working Group of RANO identified surgically related End-point evaluation problems that were not addressed in the original Macdonald criteria. Macdonald criteria led to the initiation of an International effort in Neurooncology to develop Novel Response and Progression Assessment Criteria.
In low-grade Gliomas, stereotactically guided conformal Radiotherapy should lead to a significant reduction in Radiation-associated late toxicity, while in selected groups of high-grade Gliomas the use of adjuvant or Neo-adjuvant Chemotherapy may improve survival. In primitive Neuroectodermal Tumours Prognostic Biological markers have been identified that are undergoing prospective evaluation. In infants the use of post-surgical chemotherapy alone may allow the postponing of Radiotherapy in selected cases. For patients with localized Medulloblastomas a new standard treatment is emerging that uses reduced-dose Craniospinal Radiotherapy followed by Platinum-based chemotherapy, while in Supratentorial primitive Neuroectodermal tumours future treatment will be aimed at improving local control.
Neurosurgery is a complex surgical method that presupposes the treatment, diagnosis, and rehabilitation of disorders affecting any region of the Nervous System. Some of the preponderance common Neuro surgeries are skull base surgery, Image Guided Surgery, Laser Surgery, Spinal Neurosurgery and Neurosurgical treatment.
The Global Neurosurgery market is expected to rise to 11.71% over the session of 2014-2019. Neurosurgery session includes Image Guided Surgery, Laser Surgery, Surgical operation for brain fibroadenoma, Spinal Neurosurgery, Skull base surgery, Neurosurgical treatment, Geriatric Neurosurgery, latest innovations and techniques.
The upcoming implementation of a Neurosurgical ablation device that provides controlled therapy for brain lesions those are difficult to reach and treat. This tool, will allow us to introduce the probe into the tumor and destroy it without having to perform a Surgical Operation or Craniotomy.
- Track 14-1: Brain Tumor Diagnosis
- Track 14-2: Neuroradiology
- Track 14-3: Neuroimmunology
- Track 14-4: Neuroimaging